When the serial port is not in use, a single D3 turnkey respawn can be disabled. Comment out the inittab entry with the # sign, as in:
#a1:2:respawn:d3 -n pick0 1 -t tty2
Another way to do this is to delete the entry in question, or replace the process information for a tty with a valid /etc/getty command sequence, rather than d3.
Execute the command init q to activate any changes to the inittab file.